Association of Pareidolic misidentifications, cognitive impairments,
neuropsychiatric disturbances, and Lewy body pathology in DLB and MCI-DLB 
   Lead Investigator:    Parunyou Julayanont
   Institution      :    TTUHSC, School of Medicine
   E-Mail           :    p.julayanont@ttuhsc.edu
   Proposal ID      :    1733



   Proposal Description:
   Pareidolic misidentifications are more commonly reported in patients with Lewy body dementia than in patients with other neurodegenerative conditions. This phenomenon correlates with visual hallucinations in patients with DLB. The Noise Pareidolia task was developed to evaluate the Pareidolic misidentifications and studied in patients with DLB. The objectives of this study are   1) To evaluate the association between Pareidolic misidentification and locations of Lewy body pathology   2) To assess the impairment in the Noise Pareidolia task among Lewy body-positive participants with MCI (CDR of 0.5) and normal cognition (CDR 0) comparing with the cognitively normal, Lewy-body negative participants.    3) To evaluate the impairment of the Noise Pareidolia task in DLB patients with different subtypes of cognitive impairments (executive, attention, and visuospatial/visuoperceptual impairment subtype)  4) To determine the association between the Noise Pareidolia task and neuropsychiatric symptoms in participants with DLB.